Lactoferrin and lactoferricin endocytosis halt Giardia cell growth and prevent infective cyst production
نویسندگان
چکیده
منابع مشابه
Inhibition of HSV cell-to-cell spread by lactoferrin and lactoferricin.
The milk protein lactoferrin (Lf) has multiple functions, including immune stimulation and antiviral activity towards herpes simplex virus 1 and 2 (HSV-1 and HSV-2); antiviral activity has also been reported for the N-terminal pepsin-derived fragment lactoferricin (Lfcin). The anti-HSV mode of action of Lf and Lfcin is assumed to involve, in part, their interaction with the cell surface glycosa...
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Lactoferrin (Lf) is an iron-binding glycoprotein which exhibits antibacterial activity against a broad range of Gram-negative and Gram-positive bacteria. The mechanisms of this property are complex and involve iron sequestration as well as direct interaction with bacteria. Lactoferricin (LFcin), a Lf-derived peptide released by pepsin digestion of lactoferrin, is a more potent antibacterial com...
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The purpose of this study was to determine the 50% infective dose for Giardia lamblia (CDC:0284:1) cysts in Mongolian gerbils (Meriones unguiculatus). The log10 50% infective dose results calculated by probit analysis and the Spearman-Karber method were 2.45 and 2.50, respectively.
متن کاملstudy the effects of low level laser diode on no production and healing of diabetic and cortisone acetate and normal wounded sd rats
nitric oxide (no) is a small molecule synthesized by most of mammalian cells with diverse biological activities including vasodilatation, host defense and wound healing. impaired wound healing is a common occurrence among diabetics and patients receiving glucocorticoid therapy. on the other hand the application of laser in biomedical area have been increased. thus, the current studies were desi...
15 صفحه اولTumor regression following intravenous administration of lactoferrin- and lactoferricin-bearing dendriplexes
UNLABELLED The possibility of using gene therapy for the treatment of cancer is limited by the lack of safe, intravenously administered delivery systems able to selectively deliver therapeutic genes to tumors. In this study, we investigated if the conjugation of the polypropylenimine dendrimer to lactoferrin and lactoferricin, whose receptors are overexpressed on cancer cells, could result in a...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2018
ISSN: 2045-2322
DOI: 10.1038/s41598-018-36563-1